Epidemiology and Antimicrobial Resistance Characteristics of the Sequence Type 131-H30 Subclone Among Extraintestinal Escherichia coli Collected From US Children

Epidemiology and antimicrobial resistance characteristics of the ST131-H30 subclone among extraintestinal Escherichia coli collected from US children

Escherichia coli sequence type 131 (ST131) subclone H30 as an emergent multidrug-resistant pathogen among US veterans.

BACKGROUND Escherichia coli sequence type 131 (ST131), typically fluoroquinolone-resistant (FQ-R) and/or extended-spectrum β-lactamase (ESBL)-producing, has emerged globally. We assessed its prevalence and characteristics among US veterans. METHODS In 2011, 595 de-identified E. coli clinical isolates were collected systematically within 3 resistance groups (FQ-susceptible [FQ-S], FQ-R, and ES...

Extraintestinal pathogenic Escherichia coli sequence type 131 H30-R and H30-Rx subclones in retail chicken meat, Italy.

Extraintestinal pathogenic Escherichia coli sequence type 131 (ST131), typically fluoroquinolone-resistant (FQ-R) and/or extended-spectrum β-lactamase (ESBL)-producing, has emerged globally. Among clinical isolates, ST131, primarily its H30-R and H30-Rx subclones, accounts for most antimicrobial-resistant E. coli and is the dominant E. coli strain worldwide. We assessed its prevalence and chara...

Separate F-Type Plasmids Have Shaped the Evolution of the H30 Subclone of Escherichia coli Sequence Type 131

The extraintestinal pathogenic Escherichia coli (ExPEC) H30 subclone of sequence type 131 (ST131-H30) has emerged abruptly as a dominant lineage of ExPEC responsible for human disease. The ST131-H30 lineage has been well described phylogenetically, yet its plasmid complement is not fully understood. Here, single-molecule, real-time sequencing was used to generate the complete plasmid sequences ...

Clinical and Molecular Epidemiology of Escherichia coli Sequence Type 131 ( ST 131 ) 1 among Hospitalized Patients

Clinical and Molecular Epidemiology of Escherichia coli Sequence Type 131 (ST131) 1 among Hospitalized Patients Colonized Intestinally with Fluoroquinolone-Resistant E. coli 2 3 Jennifer H. Han, MD, MSCE#; Brian Johnston, BS; Irving Nachamkin, DrPH, MPH; Pam 4 Tolomeo, MPH; Warren B. Bilker, PhD; Xiangqun Mao, PhD; Connie Clabots, MT; 5 Ebbing Lautenbach, MD, MPH, MSCE*; and James R. Johnson, M...